Khalifa, M., Attia, E., Fahim, J., Kamel, M. (2018). An overview on the chemical and biological aspects of lycorine alkaloid. Journal of advanced Biomedical and Pharmaceutical Sciences, 1(2), 41-49. doi: 10.21608/jabps.2018.4088.1016
Marwa F. Khalifa; Eman Z. Attia; John R. Fahim; Mohamed S. Kamel. "An overview on the chemical and biological aspects of lycorine alkaloid". Journal of advanced Biomedical and Pharmaceutical Sciences, 1, 2, 2018, 41-49. doi: 10.21608/jabps.2018.4088.1016
Khalifa, M., Attia, E., Fahim, J., Kamel, M. (2018). 'An overview on the chemical and biological aspects of lycorine alkaloid', Journal of advanced Biomedical and Pharmaceutical Sciences, 1(2), pp. 41-49. doi: 10.21608/jabps.2018.4088.1016
Khalifa, M., Attia, E., Fahim, J., Kamel, M. An overview on the chemical and biological aspects of lycorine alkaloid. Journal of advanced Biomedical and Pharmaceutical Sciences, 2018; 1(2): 41-49. doi: 10.21608/jabps.2018.4088.1016
An overview on the chemical and biological aspects of lycorine alkaloid
1Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt
2Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia 61111, Egypt.
Abstract
Amaryllidaceae plants are currently appreciated as a plentiful source of unique bioactive alkaloids. Among them, lycorine is one of the major pyrrolophenanthridine alkaloids commonly isolated from different species of this family. Over the past years, lycorine has attracted great research interest owing to its superlative biological potential and pharmacological actions, including antitumor, antiangiogenic, antiviral, antibacterial, antimalarial, anti-parasite, antioxidant, hepatoprotective, analgesic, anti-inflammatory activities, and inhibition of ascorbic acid synthesis, among many others. Therefore, this review was undertaken to highlight the chemical, chromatographic, spectral, and biological aspects of this promising Amaryllidaceae alkaloid, together with a future perspective for its potential application in the pharmaceutical field.