A review on the chemical and biological properties of the Amaryllidaceae alkaloid, narciprimine (1968-2020)

Boshra, Yostina Refaat; Fahim, John Refaat; Desouky, Samar

doi:10.21608/jabps.2021.74208.1128

A review on the chemical and biological properties of the Amaryllidaceae alkaloid, narciprimine (1968-2020)

Document Type : Review Articles

Authors

¹ Department of pharmacognosy, faculty of pharmacy,Minia university,Minia,Egypt

² Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt

³ department of pharmacognosy, Faculty of pharmacy, Minia, Egypt

10.21608/jabps.2021.74208.1128

Abstract

Amaryllidaceae occupies a prominent position among the most important alkaloid-rich plant families in the globe. Plants of this family show an exceptional ability to produce a myriad of structurally diverse alkaloids with noteworthy pharmacological and therapeutic potential. Of these alkaloids, narciprimine is a rare weakly basic phenanthridone alkaloid that was identified from some species belonging to the genera Cyrtanthus, Galanthus, Lycoris, Narcissus, and Zephyranthes. This alkaloid has attracted a lot of scientific attention in recent years thanks to its biological properties, including cytotoxic, anticancer, and anticholinesterase activities. Hence, this review affords a comprehensive focus on the chemical, spectral, and biological attributes of narciprimine; providing a future perspective for possible research on this valued Amaryllidaceae alkaloid.

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