Abdallah, A., Elazab, G., Mosbeh, M., Sarhan, H. (2021). Role of vitamin D and insulin resistance in polycystic ovary syndrome. Journal of Advanced Biomedical and Pharmaceutical Sciences, 4(4), 186-194. doi: 10.21608/jabps.2021.70702.1125
Aya Mohammed Abdallah; Gamal Elazab; Mohammed Hani Mosbeh; Hatem Sarhan. "Role of vitamin D and insulin resistance in polycystic ovary syndrome". Journal of Advanced Biomedical and Pharmaceutical Sciences, 4, 4, 2021, 186-194. doi: 10.21608/jabps.2021.70702.1125
Abdallah, A., Elazab, G., Mosbeh, M., Sarhan, H. (2021). 'Role of vitamin D and insulin resistance in polycystic ovary syndrome', Journal of Advanced Biomedical and Pharmaceutical Sciences, 4(4), pp. 186-194. doi: 10.21608/jabps.2021.70702.1125
Abdallah, A., Elazab, G., Mosbeh, M., Sarhan, H. Role of vitamin D and insulin resistance in polycystic ovary syndrome. Journal of Advanced Biomedical and Pharmaceutical Sciences, 2021; 4(4): 186-194. doi: 10.21608/jabps.2021.70702.1125
Role of vitamin D and insulin resistance in polycystic ovary syndrome
2clinical pharmacy department, faculty of pharmacy, Tanta university
3Obstetrics and Gynaecology department, Faculty of Medicine, Minia University
4Pharmaceutics Department, Faculty of Pharmacy, Minia University, Minia, Egypt
Abstract
Polycystic ovary syndrome (PCOS) is considered the commonest endocrinological disorder in childbearing age women with an incidence of 10%. Vitamin D has been shown in several studies to have a positive impact on female reproductive diseases, as well as PCOS. The diagnosis of PCOS, clinical symptoms, pathophysiology, hypovitaminosis D, insulin resistance, and the various methods for vitamin D and insulin assessment are all covered in this study. Androgen hypersecretion, oligo-ovulation, and/or ovarian morphologic features are used to diagnose this condition. Androgen excess, neuroendocrine causes, and insulin resistance are all part of the pathophysiology. Some female genital organs have been found to contain vitamin D receptors. Insulin regulates steroid biosynthesis in the ovaries and follicular maturation, so vitamin D is essential.
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