Elkhouly, H., Attia, E., Khedr, A., Samy, M., Fuoad, M. (2023). Investigation of the Unsaponifiable and Saponifiable Matters of Higginsia sp. sponge by GC/MS. Journal of Advanced Biomedical and Pharmaceutical Sciences, 6(2), 49-68. doi: 10.21608/jabps.2023.167962.1170
Hanaa Elkhouly; Eman Attia; Amgad Khedr; Mamdouh Nabil Samy; Mostafa Fuoad. "Investigation of the Unsaponifiable and Saponifiable Matters of Higginsia sp. sponge by GC/MS". Journal of Advanced Biomedical and Pharmaceutical Sciences, 6, 2, 2023, 49-68. doi: 10.21608/jabps.2023.167962.1170
Elkhouly, H., Attia, E., Khedr, A., Samy, M., Fuoad, M. (2023). 'Investigation of the Unsaponifiable and Saponifiable Matters of Higginsia sp. sponge by GC/MS', Journal of Advanced Biomedical and Pharmaceutical Sciences, 6(2), pp. 49-68. doi: 10.21608/jabps.2023.167962.1170
Elkhouly, H., Attia, E., Khedr, A., Samy, M., Fuoad, M. Investigation of the Unsaponifiable and Saponifiable Matters of Higginsia sp. sponge by GC/MS. Journal of Advanced Biomedical and Pharmaceutical Sciences, 2023; 6(2): 49-68. doi: 10.21608/jabps.2023.167962.1170
Investigation of the Unsaponifiable and Saponifiable Matters of Higginsia sp. sponge by GC/MS
1Pharmacognosy department faculty of pharmacy Minia university, Minia, Egypt
2Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt
3Department of Pharmacognosy, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt.
4Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt
5Faculty of Pharmacy, Minia University, Minia Egypt
Abstract
Sponges (phylum Porifera) are sessile marine filter feeders that have developed efficient defense mechanisms against foreign attackers such as viruses, bacteria, or eukaryotic organisms. Marine sponges considered to be a great source of pharmacologically of pharmacologically-active chemicals from marine organisms. Higginsia sp. (Family Desmoxyidae) was collected from the Red Sea and possesses a great number of secondary metabolites. The present study showed that, the unsaponifiable matter of Higginsia sp. contains various compounds identified as hydrocarbons (23.07%), fatty alcohols (32.32%) as well as other oxygenated compounds (21.62%). While, the saponifiable matter contains various compounds identified as methyl and ethyl esters of saturated fatty acids (34.54%) in addition to unsaturated fatty acids (35.37%) while other compounds (30.09%) couldn’t be identified. The identification of the compounds depends on the retention time and mass spectrum.
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