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Ragaa, A., Aly Hamdy, N., Fawzy, M., Hamza, N., Wally, Z. (2023). Cognitive impairment in Diabetes Mellitus. Journal of Advanced Biomedical and Pharmaceutical Sciences, 6(2), 81-85. doi: 10.21608/jabps.2023.169014.1171
Ahmed Ragaa; Nermin Aly Hamdy; Michael A Fawzy; Noran Hamza; Zahraa Wally. "Cognitive impairment in Diabetes Mellitus". Journal of Advanced Biomedical and Pharmaceutical Sciences, 6, 2, 2023, 81-85. doi: 10.21608/jabps.2023.169014.1171
Ragaa, A., Aly Hamdy, N., Fawzy, M., Hamza, N., Wally, Z. (2023). 'Cognitive impairment in Diabetes Mellitus', Journal of Advanced Biomedical and Pharmaceutical Sciences, 6(2), pp. 81-85. doi: 10.21608/jabps.2023.169014.1171
Ragaa, A., Aly Hamdy, N., Fawzy, M., Hamza, N., Wally, Z. Cognitive impairment in Diabetes Mellitus. Journal of Advanced Biomedical and Pharmaceutical Sciences, 2023; 6(2): 81-85. doi: 10.21608/jabps.2023.169014.1171

Cognitive impairment in Diabetes Mellitus

Article 3, Volume 6, Issue 2, April 2023, Page 81-85  XML PDF (414.33 K)
Document Type: Review Articles
DOI: 10.21608/jabps.2023.169014.1171
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Authors
Ahmed Ragaa email ; Nermin Aly Hamdy1; Michael A Fawzy2; Noran Hamza3; Zahraa Wally4
1Professor of Neurology, Faculty of Medicine, Minia University, Minia , Egypt
2Department of faculty of Pharmacy, Minia University, Minia, Egypt
3MARS academy
4Minia University
Abstract
Cognitive function is a broad term that refers to mental processes involved in acquiring knowledge, manipulating information, and reasoning. Preserved cognitive functioning is integral to maintaining a healthy, active, and independent lifestyle.
Both type 1 and type 2 diabetes mellitus have been linked with poor cognitive skills performance and proof of abnormalities in brain magnetic resonance imaging's structure and function. Cognitive impairment may happen at the earliest stages of diabetes and deteriorates over time, and significantly influences diabetes control and management. Cognitive impairment's pathophysiology is multifactorial. The pathophysiology might include hyperglycemia, deficiencies in insulin pathways, oxidative stress, neuroinflammation, and mitochondrial dysfunction.
Determining the mechanism of impaired cognitive skills in diabetes is crucial for developing new approaches to therapy.
This review article aims at revising our knowledge about the correlation between diabetes and cognitive impairment, emphasizing the putative underlying mechanisms.
Keywords
Cognitive impairment; Diabetes Mellitus; Inflammation
Main Subjects
Biochemistry
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