Lipid profiling, phenolic content and antioxidant activity of the endophytic fungus Alternaria sp. isolated from Dracaena plant

Ibrahim, Alyaa H.; Attia, Eman Z.; Abdelmohsen, Usama R.; Desoukey, Samar Y.; Elkhayat, Ehab S.; Fouad, Mostafa A.; Kamel, Mohamed S.

Lipid profiling, phenolic content and antioxidant activity of the endophytic fungus Alternaria sp. isolated from Dracaena plant

Document Type : Short Communication.

Authors

¹ Department of Pharmacognosy, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt

² Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt

³ Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut 71524, Egypt

⁴ Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

Abstract

The aim of this study is to present the lipid profile along with the total phenolic contents and antioxidant activities of the ethyl acetate (EtOAc) and methanol (MeOH) extracts of the endophytic fungus Alternaria sp. isolated from Dracaena sp. leaves (Family: Asparagaceae). GC/MS analysis of the petroleum ether (pet. ether) fraction demonstrated high contents of oleic (23.15%), palmitic (23.33%), and linoleic (43.92%) acids. The EtOAc and MeOH extracts displayed a high total phenolic content, which was established by the Folin-Ciocaltue method. Moreover, the EtOAc extract showed considerable free radical scavenging activity (IC50= 0.52 mg/ml) using the DPPH assay and also exhibited substantial reducing power (13.322 mg Ascorbic equiv./g dried extract) by means of the phosphomolybdate complex assay.

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