AlRasheed, M., Hammad, L., Altaweel, A., Assiri, A., Bin Ajlan, A., Almugbel, R., Aldukhail, S., Abanmy, N., Shazly, G. (2020). Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study. Journal of advanced Biomedical and Pharmaceutical Sciences, 3(2), 60-64. doi: 10.21608/jabps.2020.21568.1065
Maha M. AlRasheed; Lina F. Hammad; Abeer F. Altaweel; Alaa A. Assiri; Albatool A. Bin Ajlan; Rawan A. Almugbel; Shaikha Y. Aldukhail; Norah O. Abanmy; Gamal A. Shazly. "Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study". Journal of advanced Biomedical and Pharmaceutical Sciences, 3, 2, 2020, 60-64. doi: 10.21608/jabps.2020.21568.1065
AlRasheed, M., Hammad, L., Altaweel, A., Assiri, A., Bin Ajlan, A., Almugbel, R., Aldukhail, S., Abanmy, N., Shazly, G. (2020). 'Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study', Journal of advanced Biomedical and Pharmaceutical Sciences, 3(2), pp. 60-64. doi: 10.21608/jabps.2020.21568.1065
AlRasheed, M., Hammad, L., Altaweel, A., Assiri, A., Bin Ajlan, A., Almugbel, R., Aldukhail, S., Abanmy, N., Shazly, G. Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study. Journal of advanced Biomedical and Pharmaceutical Sciences, 2020; 3(2): 60-64. doi: 10.21608/jabps.2020.21568.1065
Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study
1Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia
2Department of Radiological Science, College of Applied Medical Sciences, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia
3Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia
4Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University 71526, Assiut, Egypt
Abstract
Background/Aims: Maintaining skin elasticity and hardness is one way of keeping younger skin. This study investigates the topical effects of Aloe Vera (AV) alone and accompanied with Omega-3 (O-3) on skin hardness and thickness. Method: Healthy females were randomly selected and divided into two groups (15 in each group) for a double-blind controlled study. All volunteers, between 18-25 years of age, were not pregnant or suffering from any medical illness. Both groups were asked to put formulations having similar appearance on the skin of forearm for 30 days. A prepared skin formulation containing AV oil only was considered baseline. The other group was treated with AV oil and O-3 mixture. Skin elasticity and hardness were measured using Digital Durometer and Diagnostic Ultrasound System. Results: Compared to baseline, skin elasticity & hardness significantly improved at the end of the study in both AV and the combination groups. There was a slight synergistic effect of combining O-3 and AV on both elasticity and hardness. Conclusion: The study is the first of its kind exploring the possible use of AV and O-3 topically to reverse the signs of aging on skin thickness. At the end of trial period improvements in skin thickness were noticed.